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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP6
All Species:
9.09
Human Site:
S249
Identified Species:
16.67
UniProt:
Q15654
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15654
NP_003293.2
476
50288
S249
H
G
P
Q
V
P
L
S
Q
P
P
E
D
E
L
Chimpanzee
Pan troglodytes
XP_001159438
612
65827
S386
G
P
S
S
V
A
P
S
F
R
P
E
D
E
L
Rhesus Macaque
Macaca mulatta
XP_001106127
476
50267
S249
H
G
P
Q
V
H
L
S
Q
P
P
E
D
E
L
Dog
Lupus familis
XP_536859
478
50671
N251
Y
G
P
Q
V
P
L
N
Q
P
P
E
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Y4
480
50915
G253
H
E
P
Q
G
P
L
G
Q
P
P
E
E
E
L
Rat
Rattus norvegicus
Q5XI07
632
68242
S406
G
P
P
S
V
P
P
S
F
R
P
E
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506023
531
55801
P319
P
G
G
K
E
D
R
P
R
G
A
H
P
I
G
Chicken
Gallus gallus
Q5F464
604
65121
A378
G
P
T
S
S
T
P
A
F
R
P
E
D
E
L
Frog
Xenopus laevis
A5H447
663
70707
K395
G
A
Q
S
T
G
G
K
D
M
K
P
L
P
E
Zebra Danio
Brachydanio rerio
A8DZE6
648
70883
P409
T
P
S
R
D
S
G
P
S
Q
A
E
R
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396072
477
52619
V253
P
Q
G
K
V
S
P
V
K
E
V
D
V
L
T
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
A207
Y
T
C
C
E
C
G
A
E
L
G
Q
R
P
F
Sea Urchin
Strong. purpuratus
XP_798292
448
48550
K225
Q
P
I
T
S
P
A
K
S
G
A
E
A
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.1
98.3
89.3
N.A.
86.4
41.7
N.A.
58.5
43.3
30.4
28.7
N.A.
N.A.
36.6
21.4
39.9
Protein Similarity:
100
53.7
98.5
92.2
N.A.
90.2
51.2
N.A.
64.2
53.1
42.6
42.7
N.A.
N.A.
49
35.7
51.6
P-Site Identity:
100
46.6
93.3
80
N.A.
73.3
60
N.A.
6.6
33.3
0
13.3
N.A.
N.A.
6.6
0
20
P-Site Similarity:
100
46.6
93.3
100
N.A.
80
60
N.A.
20
40
0
20
N.A.
N.A.
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
8
16
0
0
24
0
8
0
0
% A
% Cys:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
0
0
8
0
0
8
39
0
0
% D
% Glu:
0
8
0
0
16
0
0
0
8
8
0
70
16
62
8
% E
% Phe:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
8
% F
% Gly:
31
31
16
0
8
8
24
8
0
16
8
0
0
0
8
% G
% His:
24
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
0
0
16
0
0
0
16
8
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
31
0
0
8
0
0
8
8
62
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
16
39
39
0
0
39
31
16
0
31
54
8
8
16
0
% P
% Gln:
8
8
8
31
0
0
0
0
31
8
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
8
24
0
0
16
8
0
% R
% Ser:
0
0
16
31
16
16
0
31
16
0
0
0
0
0
0
% S
% Thr:
8
8
8
8
8
8
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
47
0
0
8
0
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _